产品货号:
Z14518
中文名称:
FAIM2抗体
英文名称:
Anti-FAIM2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-FAIM2 Antibody |
指标别名 | LFG,LFG2,NGP35,NMP35,TMBIM2,KIAA0950,LFG,Protein lifeguard 2,Fas apoptotic inhibitory molecule 2 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC |
基因名称 | FAIM2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | FAIM2 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human FAIM2.The immunogen is located within the first 50 amino acids of FAIM2. |
计算分子量 | 35kDa |
成分 | FAIM2 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | FAIM2 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Programmed cell death regulates a number of biological processes such as normal organism development,tissue homeostasis,and removal of damaged cells.Disruption of this process has been implicated in a variety of diseases such as cancer.FAIM2 is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal.In this respect,FAIM2 is functionally similar to the anti-apoptotic proteins FAIM,FLIP and Bcl-xL.FAIM2,a seven membrane spanning protein,can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas.FAIM2 is widely distributed,but highly expressed in the hippocampus and other neural tissues.FAIM2 was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway. |
Uniprot ID | Q9BWQ8 |
基因名全称 | Fas apoptotic inhibitory molecule 2 |
蛋白名全称 | Fas apoptotic inhibitory molecule 2 |
推荐稀释比 | FAIM2 antibody can be used for detection of FAIM2 by Western blot at 0.5 ~ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in mouse samples and Immunohistochemistry in mouse samples.All other applications and species not yet tested. |
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